Authorities said two USPS employees were fatally shot Tuesday at a Memphis mail facility, and a third employee described as the shooter died from a self-inflicted gunshot.
In recent weeks, there have been three high-profile shootings in or near west Tennessee community.
The three postal workers were found dead following the shooting at the East Lamar Carrier Annex in a renowned Memphis area, US Postal Inspector Susan Link.
According to Lisa-Anne Culp of the Federal Bureau of Investigation, the shooting was carried out by a third postal worker who shot himself.
Link and Culp did not reveal their identities or motives during a brief news conference late Tuesday afternoon.
The incident took place inside a post office in Memphis' historic Orange Mound area, southeast of the city. Employees are the only ones who use the carrier annex.
Following the incident, police shut the street leading to the facility, and the Federal Bureau of Investigation, the United States Postal Inspection Service, and other federal agencies responded to investigate.
People watching the police activity talked near a convenience store at an intersection. Officers had blocked the street with yellow crime scene tape and barricades nearby. As they drove past officers and reporters, some cars slowed down.
A white four-door automobile was hauled away from the scene, but its owner was unknown.
"The Postal Service is devastated by today's events in Memphis," the company said in a statement. "Our thoughts are with the family members, friends, and coworkers."
Other shootings in the Memphis region have occurred in recent weeks. According to police, the franchise owner of a sushi counter inside a Kroger grocery store in the Collierville suburb of Collierville fatally shot one person and wounded 14 others before killing himself on Sept. 23.
A teenage boy was shot and seriously injured inside a Memphis school a week later, and police detained a second boy suspected of being the shooter.
Congressman Steve Cohen, a Democrat from Memphis, called the post office "the latest site of gun violence" in the city.
Tuesday's incident comes 11 years after another fatal post office shooting in West Tennessee.